Yoshiaki Amakura Selected Research

Ephedrine

1/2020	Quality Evaluation and Characterization of Fractions with Biological Activity from Ephedra Herb Extract and Ephedrine Alkaloids-Free Ephedra Herb Extract.
1/2019	Analgesic Effects of Ephedra Herb Extract, Ephedrine Alkaloids-Free Ephedra Herb Extract, Ephedrine, and Pseudoephedrine on Formalin-Induced Pain.
1/2019	[The Adverse Effects of Ephedra Herb and the Safety of Ephedrine Alkaloids-free Ephedra Herb Extract (EFE)].
1/2018	Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
7/2016	Ephedrine alkaloids-free Ephedra Herb extract: a safer alternative to ephedra with comparable analgesic, anticancer, and anti-influenza activities.

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Yoshiaki Amakura Research Topics

Disease

6	Neoplasms (Cancer) 05/2021 - 11/2013
5	Inflammation (Inflammations) 01/2021 - 05/2013
5	Ischemia 01/2019 - 10/2012
4	Human Influenza (Influenza) 01/2020 - 07/2016
4	Body Weight (Weight, Body) 10/2017 - 01/2014
3	Brain Ischemia (Cerebral Ischemia) 07/2018 - 10/2012
2	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2019 - 01/2018
2	Pain (Aches) 01/2019 - 07/2016
1	Obesity 12/2021
1	Infections 05/2021
1	Cognitive Dysfunction 01/2021
1	Adenocarcinoma 01/2021
1	Colonic Neoplasms (Colon Cancer) 01/2021
1	Hiccup (Hiccups) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Dysuria 01/2019
1	Reperfusion Injury 07/2018
1	Hypokalemia 01/2018
1	Atrial Fibrillation 01/2018
1	Leukemia 04/2016
1	Autoimmune Diseases (Autoimmune Disease) 04/2014
1	Hypersensitivity (Allergy) 04/2014
1	Breast Neoplasms (Breast Cancer) 11/2013
1	Neuroinflammatory Diseases 05/2013
1	Celiac Disease (Celiac Sprue) 12/2012
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2012
1	Rheumatoid Arthritis 12/2012
1	Hyperammonemia 12/2006
1	Hypercalcemia (Milk Alkali Syndrome) 12/2006
1	Hypocalcemia 12/2006
1	Brain Diseases (Brain Disorder) 12/2006

Drug/Important Bio-Agent (IBA)

6	Ephedrae herbaIBA 01/2020 - 11/2013
5	Ephedrine FDA LinkGeneric 01/2020 - 07/2016
5	Analgesics (Analgesic Drugs)IBA 01/2020 - 07/2016
5	AlkaloidsIBA 01/2020 - 07/2016
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 10/2017 - 10/2012
4	3,3',4',5,6,7,8-heptamethoxyflavoneIBA 04/2016 - 10/2012
3	oenothein BIBA 12/2021 - 05/2013
3	Neuroprotective AgentsIBA 01/2020 - 05/2014
3	FlavonoidsIBA 04/2016 - 10/2012
3	LipopolysaccharidesIBA 04/2015 - 05/2013
2	ellagitanninIBA 05/2021 - 04/2016
2	Nerve Growth Factors (Neurotrophins)IBA 01/2021 - 10/2012
2	Phosphotransferases (Kinase)IBA 01/2020 - 10/2017
2	Formaldehyde (Formol)FDA Link 01/2019 - 07/2016
2	auraptenIBA 01/2019 - 01/2014
2	naringinIBA 01/2019 - 07/2018
2	PowdersIBA 01/2019 - 01/2014
2	Pseudoephedrine FDA LinkGeneric 01/2019 - 07/2016
2	Calcium-Calmodulin-Dependent Protein KinasesIBA 07/2018 - 10/2017
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 07/2016 - 11/2013
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 07/2016 - 11/2013
1	FructoseIBA 12/2021
1	ethyl acetateIBA 01/2021
1	AcetoneIBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Ellagic AcidIBA 01/2021
1	Ointments (Pastes)IBA 01/2021
1	glansreginin AIBA 01/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2018
1	Glutathione (Reduced Glutathione)IBA 07/2018
1	Epinephrine (Adrenaline)FDA LinkGeneric 01/2018
1	Proteins (Proteins, Gene)FDA Link 10/2017
1	U 0126 (UO 126)IBA 10/2017
1	MitogensIBA 10/2017
1	CorticosteroneIBA 04/2016
1	FlavonesIBA 04/2015
1	flavoneIBA 04/2015
1	Messenger RNA (mRNA)IBA 04/2015
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 04/2014
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2014
1	Tyrosine (L-Tyrosine)FDA Link 11/2013
1	herbacetinIBA 11/2013
1	Proto-Oncogene Proteins c-metIBA 11/2013
1	TanninsIBA 12/2012
1	Intermediate Filament ProteinsIBA 10/2012
1	Glial Fibrillary Acidic ProteinIBA 10/2012
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 10/2012
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 10/2012
1	Vitamin D FDA LinkGeneric 12/2006

Therapy/Procedure

3	Oral Administration 01/2019 - 07/2016
1	Kampo Medicine (Kampo) 01/2021
1	Analgesia 01/2019
1	Therapeutics 11/2013